JAPANESE 
Hiroshi Sakamoto, Ph.D.
Professor, Division of Biosignal Transduction, Gene Expression
Research Focus
Biological Functions of RNA-binding Proteins and Chromatin-associated Factors
Recent Publications
- Miwa, T., Ohtani, K., Inoue, K., Sakamoto, H. (2022)
The germ cell-specific TAP-like protein NXF-2 forms a novel granular structure and is required for tra-2 3'UTR-dependent mRNA export in Caenorhabditis elegans.
Genes to Cells 27, 621-628. - Miwa, T., Inoue, K., & Sakamoto, H. (2019)
MRG-1 is required for both chromatin-based transcriptional silencing and genomic integrity of primordial germ cells in C. elegans.
Genes to Cells 24, 377-389. - Miwa, T., Takasaki, T., Inoue, K., & Sakamoto, H. (2015)
Restricted distribution of mrg-1 mRNA in C. elegans primordial germ cells through germ granule-independent regulation.
Genes to Cells 20, 932-942. - Shiimori, M., Inoue, K. & Sakamoto, H. (2013)
A specific set of EJC subunits is required for the nuclear retention of unspliced RNAs in C. elegans.
Mol. Cell. Biol. 33, 444-456. - Fujiwara,T., Fukao, A., Sasano, Y., Matsuzaki, H., Kikkawa, U., Imataka, A.,
Inoue, K., Endo, S., Sonenberg, N. Thoma, C. & Sakamoto, H. (2012)
Functional and direct interaction between the RNA binding protein HuD and active Akt1.
Nucleic Acids Res. 40, 1944-1953. - Fukao, A., Sasano, Y., Imataka, H., Inoue, K., Sakamoto, H., Sonenberg, N., Thoma, C & Fujiwara, T. (2009)
The ELAV protein HuD stimulates cap-dependent translation in a poly(A)- and eIF4A-dependent manner.
Mol. Cell 36, 1007-1017. (see also Preview by Chen & Shyu in Mol. Cell Dec. 24) - Takasaki, T., Liu, Z., Habara, Y., Nishiwaki, K., Nakayama, J., Inoue, K., Sakamoto, H. & Strome, S. (2007)
MRG-1, an autosome-associated protein, silences X-linked genes and protects germline immortality in Caenorhabditis elegans.
Development 134, 757-767. (see also In This Issue in Development Feb. 15)
Contact (H. Sakamoto)
Office: Grad. Sch. Sci. Tech. Bldg 1, Room 404
Tel: +81-78-803-5796
FAX: +81-78-803-5720
E-mail: hsaka@kobe-u.ac.jp